In 2025, multilateralism has been under more pressure than ever, even as cross-border threats surge.On the sidelines of UNGA 80, Pandemic Action Network (PAN), the Independent Panel for Pandemic Preparedness and Response, the Elders, the Africa-Europe Foundation, and Resilience Action Network Africa (RANA) will explore what’s needed to rebuild and refocus multilateralism and galvanize leadership, action, and investment for the interconnected, pressing threats of our time.